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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Invest Dermatol. 2018 May 9;138(11):2470–2479. doi: 10.1016/j.jid.2018.04.024

Figure 2. Dsg2 promotes cutaneous wound healing.

Figure 2

(a) Full-thickness wounds were inflicted on the dorsal skin of wild-type and K14-Dsg2 transgenic mice and photographed up to 4 days post-wounding. Space between blue ruler lines is 1 mm. (b) H&E staining of 4-day old wild-type and transgenic wounds. Dashed lines demarcate wound edge. Scale bar=100 μm (c) Wound area of non-epithelialized tissue was measured in ImageJ (mm2) and normalized to the area of fresh wounds. Data are expressed as average relative area of re-epithelialized tissue covering the initial wound (mm2) ± SEM. N=13 wild-type; 16 transgenic. (d) Representative immunofluorescence of wound-adjacent wild-type and transgenic mouse skin 4 days post wounding for PCNA (green) and DAPI (blue). Scale bars=50 μm.