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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Exp Hematol. 2018 Aug 17;67:18–31. doi: 10.1016/j.exphem.2018.08.004

Figure 5. Comparison of long term engraftment of mature and stem human hematopoietic cells in unconditioned NRG and NRGS mice.

Figure 5.

(A) Representative flow plots and relative percentages of human stem (huCD45+/huCD34+) and mature (huCD45+/huCD34-) hematopoietic cells in the spleens of unconditioned NRG (n=5) and NRGS (n=5) mice 105 days post transplantation of 5 × 10^5 human CD34+ UBC cells, indicating significantly higher engraftment of both stem and mature human hematopoietic cells. (B) Representative flow plots and relative percentages of mature and stem human hematopoietic cells detected in the bone marrow of unconditioned NRG and NRGS mice, showing highly significant enrichment of both stem and mature human hematopoietic cells selectively in NRGS mice.