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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Immunol. 2018 Sep 28;201(9):2612–2623. doi: 10.4049/jimmunol.1700808

Figure 4. Helminth-induced generation of active TGFβ requires STAT6.

Figure 4.

Mesenteric lymph node (MLN) T cells from Hpb-infected and uninfected 8–9 week-old male STAT6–/– or WT (BALB/c) mice were cultured in vitro with plate-bound anti-CD3 and soluble anti-CD28 for 48 hours. Supernatants were analyzed for TGFβ cytokine content by ELISA. Dot plot distribution with mean of multiple samples (N) with each dot representing the mean for a single sample from multiple determinations (≥3) and each bar representing the mean from multiple samples; p values are provided in each panel.