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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Immunol. 2018 Sep 28;201(9):2700–2709. doi: 10.4049/jimmunol.1701666

Figure 5.

Figure 5.

Efficacy of FH6,7/Fc against N. gonorrhoeae OC7 in the mouse vaginal colonization model of gonorrhea. Premarin®-treated wild-type BALB/c mice were given 6 × 105 CFU strain OC7 intravaginally on Day 0. Mice (n=10/group) were given either FH6,7/Fc or PBS (control) daily, beginning on Day 0 through Day 8, when the experiment was terminated. A. Kaplan Meier curves showing time to clearance of infection. P<0.0001 by Mantel-Cox log-rank test. B. Log10 CFU versus time. X-axis, day; Y-axis, log10 CFU. C. Bacterial burdens consolidated over time (Area Under the Curve [log 10 CFU] analysis) for the two groups. Comparison was made using the Mann-Whitney (non-parametric) test.