Table 3. Daily intake of energy, fat, carbohydrates, protein, minerals, and vitamins related to bone metabolism during the treatment period.

	Group	Treatment period
		Baseline	12 weeks	24 weeks
Energy (kcal/day)	Placebo	1,718 ± 469	1,638 ± 337	1,662 ± 460
	C-3102	1,574 ± 536	1,463 ± 402	1,470 ± 453
Fat (g/day)	Placebo	56 ± 16	57 ± 14	55 ± 17
	C-3102	49 ± 19*	49 ± 18*	46 ± 17
Carbohydrates (g/day)	Placebo	227 ± 67	204 ± 50	218 ± 67
	C-3102	208 ± 83	186 ± 58	193 ± 66
Protein (g/day)	Placebo	64 ± 17	63 ± 16	63 ± 21
	C-3102	63 ± 27	57 ± 17	59 ± 23
Calcium (mg/day)	Placebo	506 ± 185	499 ± 181	480 ± 180
	C-3102	480 ± 243	478 ± 189	464 ± 268
Magnesium (mg/day)	Placebo	231 ± 68	220 ± 50	226 ± 67
	C-3102	228 ± 85	212 ± 54	215 ± 79
Phosphorus (mg/day)	Placebo	971 ± 279	955 ± 253	947 ± 317
	C-3102	938 ± 406	881 ± 271	895 ± 399
Vitamin C (mg/day)	Placebo	109 ± 49	95 ± 30	113 ± 48
	C-3102	108 ± 53	90 ± 44	107 ± 46
Vitamin D (mg/day)	Placebo	10 ± 5	12 ± 5	11 ± 6
	C-3102	14 ± 16	12 ± 9	12 ± 11
Vitamin K (mg/day)	Placebo	254 ± 108	235 ± 80	250 ± 108
	C-3102	253 ± 135	242 ± 107	226 ± 120

Values are means ± SDs. Significant differences were determined by Student’s t-test. *p<0.05 vs. placebo group.