Table 1. Comparison of general characteristics between case and control groups.
| Factors | Case group (n=346) | Control group (n=480) | χ2/t | P |
|---|---|---|---|---|
| Gender | 0.516 | 0.472 | ||
| Male | 170 (49.1%) | 248 (51.7) | ||
| Female | 176 (50.9%) | 232 (48.3) | ||
| Age | 57.1 ± 7.0 | 56.6 ± 7.0 | −1.086 | 0.278 |
| BMI | 23.6 ± 3.0 | 23.8 ± 3.1 | 0.622 | 0.534 |
| Course of disease | 1.2 ± 0.8 | 1.1 ± 0.7 | 1.907 | 0.056 |
| Smoking | 3.352 | 0.067 | ||
| Yes | 114 (32.9%) | 188 (39.2%) | ||
| No | 232 (67.1%) | 292 (60.8%) | ||
| Drinking | 0.725 | 0.394 | ||
| Yes | 100 (28.9%) | 152 (31.7%) | ||
| No | 246 (71.1%) | 328 (68.3%) | ||
| Kellgren–Lawrence grading | - | |||
| I/II | 206 (59.5%) | |||
| III/IV | 140 (40.5%) | |||
| ESR ≥ 20 | 180 (52.0%) | - | ||
| CRP > 8 mg/l | 229 (66.2%) | - | ||
| rs4747096 | 28.110 | 0.000 | ||
| AA | 146 (42.2%) | 256 (53.3%) | ||
| AG | 126 (36.4%) | 182 (37.9%) | ||
| GG | 74 (21.4%) | 42 (8.8%) |