Table 2. Logistic regression analysis of associations between ADAMTS14/rs4747096 gene polymorphism and KOA.
| Genotype | Cases | Control | OR (95% CI) | P | aOR (95%CI) | aP | ||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | |||||
| GG compared with AA | 74/146 | 21.4/42.2 | 42/256 | 8.8/53.3 | 3.09 (2.01–4.75) | 0.000 | 3.26 (2.11–5.04) | 0.000 |
| GG compared with AG | 74/126 | 21.4/36.4 | 42/182 | 8.8/37.9 | 2.55 (1.64–3.96) | 0.000 | 2.57 (1.65–4.02) | 0.000 |
| GG/AG compared with AA | 200/146 | 57.8/42.2 | 224/256 | 46.7/53.3 | 1.57 (1.19–2.07) | 0.002 | 1.60 (1.21–2.12) | 0.001 |
| GG compared with AG/AA | 74/272 | 21.4/78.6 | 42/438 | 8.8/91.2 | 2.84 (1.89–4.27) | 0.000 | 2.98 (1.98–4.51) | 0.000 |
| G compared with A | 274/418 | 39.6/60.4 | 266/694 | 27.7/72.3 | 1.71 (1.39–2.11) | 0.000 | - | - |
Abbreviation: aP, adjusted P value; aOR, adjust OR: adjust age, gender, smoking, drinking, and BMI.