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. 2018 Oct 23;38(5):BSR20181413. doi: 10.1042/BSR20181413

Table 3. Subgroup analyses between ADAMTS14/rs4747096 gene polymorphism and the risk of KOA.

Variables rs4747096 (Case/control) GG compared with AA GG compared with AG GG/AG compared with AA GG compared with AG/AA G compared with A
AA AG GG OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P OR (95%CI) P
Sex
 Male 73/132 63/96 34/20 3.07 (1.65–5.73) 0.020 2.59 (1.37–4.89) 0.003 1.51 (1.02–2.24) 0.039 2.85 (1.58–2.15) 0.001 1.66 (1.24–2.23) 0.001
 Female 73/124 63/86 40/22 3.09 (1.70–5.60) 0.000 2.48 (1.34–4.58) 0.004 1.62 (1.09–2.41) 0.017 2.80 (1.60–4.93) 0.000 1.76 (1.31–2.36) 0.000
Age (years)
  <60 78/156 82/118 50/28 3.57 (2.09–6.11) 0.000 2.57 (1.50–4.42) 0.001 1.28 (0.82–2.01) 0.277 3.05 (1.85–5.05) 0.000 1.89 (1.46–2.45) 0.000
  ≥60 68/100 40/64 24/14 2.52 (1.22–5.22) 0.013 2.49 (1.16–5.35) 0.019 1.81 (1.26–2.59) 0.001 2.51 (1.25–5.06) 0.010 1.43 (1.01–2.03) 0.042
Smoking
  Yes 42/108 41/60 31/10 2.78 (1.57–4.93) 0.000 2.81 (1.57–5.03) 0.001 2.31 (1.43–3.73) 0.001 2.79 (1.62–4.82) 0.000 2.89 (2.01–4.15) 0.000
  No 104/148 85/122 43/22 3.99 (2.05–7.76) 0.000 2.27 (1.14–4.51) 0.020 1.26 (0.90–1.79) 0.183 3.14 (1.69–5.84) 0.000 1.47 (1.13–1.91) 0.004
Drinking
  Yes 40/80 40/52 20/10 4.08 (2.35–7.07) 0.000 3.71 (2.11–6.53) 0.000 1.53 (1.10–2.13) 0.012 3.91 (2.31–6.63) 0.000 1.77 (1.38–2.28) 0.000
  No 106/176 86/130 54/22 2.00 (0.96–4.14) 0.062 1.30 (0.62–2.73) 0.490 1.67 (1.00–2.78) 0.050 1.65 (0.84–3.25) 0.148 1.47 (0.98–2.22) 0.063
BMI
  ≥24 63/98 55/74 27/18 3.72 (2.13–6.52) 0.000 2.97 (1.68–5.30) 0.000 1.70 (1.18–2.45) 0.004 2.19 (1.15–4.15) 0.017 0.93 (0.66–1.30) 0.677
  <24 83/158 71/108 47/48 2.33 (1.19–4.58) 0.014 2.02 (1.01–4.03) 0.046 1.39 (0.90–2.14) 0.140 3.38 (1.99–5.75) 0.000 1.18 (0.90–1.55) 0.219