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. 2018 Oct 24;8:15703. doi: 10.1038/s41598-018-33989-5

Table 1.

Distribution of potential confounders among men with and without vasectomy.

Total
(N = 2425)
With vasectomy (N = 485) Without vasectomy (N = 1940) P value
Age and anthropometric measures
Age (years) 58.3 ± 8.5 58.4 ± 8.5 58.3 ± 8.4 0.85
Height (cm) 164.2 ± 6.7 162.9 ± 6.7 164.6 ± 6.7 <0.001
Weight (kg) 64.7 ± 11.3 63.9 ± 11.6 64.9 ± 10.9 0.07
BMI (kg/m2) 23.9 ± 3.4 23.97 ± 3.63 23.9 ± 3.6 0.77
AC (cm) 85.4 ± 11.4 85.1 ± 11.4 85.4 ± 11.4 0.51
Smoking status - no./total (total no. (%)) 0.72
   Never smoked 795 (32.8) 147 (30.6) 648 (33.4)
   Former smoker 301 (12.4) 56 (11.5) 245 (12.6)
   Current smoker 1329 (54.8) 281 (57.9) 1048 (54.0)
Alcohol intake (total no. (%)) 0.72
   None 717 (29.6) 132 (27.2) 585 (30.2)
   1–4 days/wk 1348 (55.6) 267 (55.1) 1081 (55.7)
   ≥5 days/wk 360 (14.8) 86 (17.7) 274 (14.1)
Education (total no. (%)) 0.92
   0–9 years 1006 (41.4) 214 (44.1) 792 (40.8)
   >10 years 1419 (58.6) 271 (55.9) 1148 (59.2)
Residence no./total (total no. (%)) <0.001
   township 754 (31.1) 101 (20.8) 653 (33.7)
   village 1671 (68.9) 384 (79.1) 1287 (66.3)
   Married 2239 (92.3) 455 (93.8) 1784 (91.9) 0.17
Health status
AMS 30.62 ± 9.74 31.27 ± 10.16 30.45 ± 9.63 0.58
SF-36 score 539.96 ± 132.00 524.17 ± 133.02 543.90 ± 131.48 0.45
IPSS 6.50 ± 7.68 6.92 ± 7.46 6.40 ± 7.73 0.79
Score on Beck Depression Inventory 3.51 ± 4.83 3.93 ± 5.39 3.41 ± 4.67 0.01
Hormone levels
TT (nmol/l) 16.16 ± 5.59 16.36 ± 6.01 16.11 ± 5.36 0.02
LH (U/l) 6.46 ± 4.76 6.78 ± 5.31 6.38 ± 4.57 0.07
SHBG (nmol/l) 49.86 ± 24.36 50.27 ± 24.99 49.74 ± 24.2 0.31
cFT (nmol/l) 0.26 ± 0.09 0.27 ± 0.12 0.26 ± 0.08 0.67
FTI 0.37 ± 0.15 0.37 ± 0.15 0.37 ± 0.15 0.56
TSI 3.30 ± 1.94 3.27 ± 1.95 3.3 ± 1.93 0.47
fPSA (mmol/l) 0.29 ± 0.52 0.38 ± 1.09 0.27 ± 0.25 <0.01
Glucose (mmol/l) 5.22 ± 1.47 4.98 ± 1.36 5.27 ± 1.49 0.49
Cholesterol (mmol/l) 5.38 ± 1.15 5.28 ± 1.14 5.37 ± 1.19 0.09
Triglyceride (mmol/l) 1.70 ± 1.75 1.89 ± 2.05 1.82 ± 1.8 0.01
HDL (mmol/l) 1.56 ± 0.53 1.64 ± 0.5 1.66 ± 0.52 0.80
Total protein (mmol/l) 80.94 ± 7.49 79.32 ± 6.3 81.24 ± 7.66 <0.01

BMI = body mass index; AC: abdomen circumference; AMS: aging males’ symptoms; TT = total testosterone; LH = luteinizing hormone; SHBG = sex hormone-binding globulin; cfT = calculated free testosterone; FTI = free testosterone index; TSI = testosterone secreting index; fPSA: free prostate specific antigen; HDL = high-density lipoprotein cholesterol; Statistical significance is set at p < 0.05.