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. 2018 Oct 25;9(10):200. doi: 10.1038/s41424-018-0068-6

Table 4.

Impact level of physical activity and risk of fecal incontinence

MET hours/week categorya
Lowest Highest
High-impact activity b
 Person-years of follow-up 132,185 43,262
 No. of cases 4652 1302
 Age-adjusted HR (95% CI) 1.00 0.99 (0.93–01.06)
 Multivariate-adjusted HR without mediators (95% CI)c 1.00 1.00 (0.94–1.06)
 Multivariate-adjusted HR (95% CI)d 1.00 1.01 (0.95–1.08)
Low-impact activity b
 Person-years of follow-up 87,145 88,298
 No. of cases 3420 2534
 Age-adjusted HR (95% CI) 1.00 0.80 (0.76–0.84)
 Multivariate-adjusted HR without mediators (95% CI)c 1.00 0.81 (0.77–0.85)
Multivariate-adjusted HR (95% CI)d 1.00 0.84 (0.79–0.88)

High-impact activities sum of MET hours/week from high-impact activities (jogging, running, tennis, aerobics), low-impact activities all other MET hours/week that were not high-impact

aLowest category is below the 50th percentile (0 MET hours/week for high-impact activities, <10.1 MET hours/week for high impact activities), highest category above the 50th percentile (>0 METs/week for high-impact activities, >10 for low-impact activities)

bHigh-impact activity and low-impact activity are adjusted for each other in all models

cModel as below with potential mediators between physical activity and fecal incontinence (BMI, hypertension, diabetes mellitus) excluded

dModels adjusted for age (months), race, smoking (never, past, current), BMI (<18.5, 18.5–24.9, 25–29.9, 30–34.9, ≥35 kg/m2), menopausal hormone therapy use (never, past, current), parity (number of live births), hypertension (yes/no), diabetes mellitus (yes/no), neurologic disease (yes/no), and history of cholecystectomy (yes/no)