Table 1.
Crystal and structure refinement data of matrine derivatives 1–2.
| Matrine derivative | 1 | 2 |
|---|---|---|
| Empirical formula | C23H29N3O | C21H35N3O |
| Formula weight | 363.5 | 345.53 |
| Temperature (K) | 293(2)K | 273(2)K |
| Wavelength (A°) | 1.54178 | 1.54178 |
| Crystal system | orthorhombic | orthorhombic |
| Space group | P21 | P21 |
| a (Å) | 8.62130(10) | 12.38460(10) |
| b(Å) | 18.25770(10) | 31.5861(3) |
| c(Å) | 25.6873(2) | 5.292 |
| α(°) | 90 | 90 |
| β(°) | 90 | 117.825(4) |
| γ(°) | 90 | 90 |
| V (A° 3) | 4043.31(6) | 2070.13(3) |
| Z | 8 | 1 |
| Dc (g cm−3) | 1.253 | 1.167 |
| Mu (Mo Kα) (mm) | 0.636 | 0.587 |
| F (000) | 1648 | 800 |
| Crystal size (mm) | 0.36 × 0.30 × 0.20 | 0.28 × 0.20 × 0.1 |
| Reflections collected | 38567 | 15404 |
| Independent reflection | 8120[R(int) = 0.0391] | 4131[R(int) = 0.0351] |
| Goodness-of-fit on F2 | 1.001 | 1.066 |
| Final R indices [I > 2σ(I)] | R1 = 0.0305, ωR2 = 0.0807 | R1 = 0.0380, ωR2 = 0.1026 |
| R indices (all data) | R1 = 0.0318, ωR2 = 0.0793 | R1 = 0.0388, ωR2 = 0.1019 |