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. 2018 Oct 24;8:15686. doi: 10.1038/s41598-018-33908-8

Table 4.

IC50 of matrine derivatives 1 and 2 against Hela229 cells.

Compounds IC50 (mmol/L)
24 h 48 h 72 h
Sophocarpine 1.69 ± 0.30 1.64 ± 0.24 1.50 ± 0.80
Matrine 1.71 ± 0.19 1.64 ± 0.54 1.53 ± 0.32
Matrine derivatives 1 0.75 ± 0.10 0.52 ± 0.06 0.42 ± 0.12
Matrine derivatives 2 0.87 ± 0.26 0.91 ± 0.17 0.12 ± 0.03