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. 2018 Sep 12;16(5):3987–3995. doi: 10.3892/etm.2018.6732

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — miR-520b regulates proliferation and metastasis of non-small cell lung cancer through targeting Rab22A. The reversal effects of Rab22A on miR-520b mimic-transfected cell functions were analyzed. (A) A549 cells overexpressed Rab22A. (B) Expression levels of Rab22A were detected by western blot analysis. (C) Cell proliferation was assessed via a cell counting kit-8 assay. (D) Cell cycle was detected with flow cytometry. (E) Cell invasion and migration abilities were assessed with Transwell chamber assay (magnification, ×100). *P<0.05 vs. NC; ^#P<0.05 vs. miR-520b mimics. miR, microRNA; NC, normal control; OD, optical density.