Figure 1.

PDGF-BB treatment promotes HCASMC proliferation and inhibits miR-365b-3p expression. HCASMCs were treated with PDGF-BB for 6 h. (A) Cell proliferation of HCASMCs was measured using the CCK-8 assay. (B) Reverse transcription-quantitative polymerase chain reaction was conducted to evaluate miR-365b-3p expression levels. *P<0.05, **P<0.01 and ***P<0.001 vs. Control. PDGF-BB, platelet-derived growth factor-BB. HCASMCs, human coronary artery smooth muscle cells; miR, microRNA; OD, optical density.