Table II.
Dose | Administration | Days | |
---|---|---|---|
AA (R4 + rituximab) | |||
Cyclophosphamide | 800 mg/m2 | IV over 2 h | D1 |
Cyclophosphamide | 200 mg/m2 | IV over 1 h | D2, 3, 4 |
Vindesine | 3 mg/m2 (max 5 mg) | IV | D1 |
Doxorubicin | 20 mg/m2 | IV over 2 h | D2, D3 |
Cytarabine | 2,000 mg/m2 | IV over 3 h | D4 (q12 h) |
Prednisone | 60 mg/m2 | Per os | D1-7 |
Triple sheath note (dose by age) | D1, D8 | ||
BB (R4 + rituximab) | |||
Ifosfamide | 1,200 mg/m2 | IV over 2 h | D1-5 |
Mesna 400 mg/m2, | |||
0, +4, +8 h | |||
Etoposide | 100 mg/m2 | IV over 2 h | D3-5 |
Methotrexate | 5,000 mg/m2 | IV over 24 h | D1 |
Vindesine | 3 mg/m2 (max 5 mg) | IV | D1 |
Prednisone | 60 mg/m2 | Per os | D1-7 |
Triple sheath note (dose by age) | D1, D8 |