TABLE 1.
Characteristics of patients with PVCRBSI
| Parameter | Value for the parameter (n = 711)a |
|---|---|
| Median age (range [yr]) | 67 (55–77) |
| Male sex | 467 (65.7) |
| Phlebitis | 636 (89.5) |
| Catheter culture | |
| Negative | 12 (1.7) |
| Positive | 154 (21.7) |
| Not performed | 545 (76.7) |
| Prior hospital admission | 99 (13.9) |
| Days since hospital admission | |
| Median no. of days (range) | 7 (4–12) |
| 0–7 | 390 (54.9) |
| 8–14 | 161 (22.6) |
| 15–21 | 60 (8.4) |
| >21 | 68 (9.6) |
| Unknown | 32 (4.5) |
| Days since catheter placement | |
| Median no. of days (range) | 5 (3–7) |
| 0–3 | 201 (28.3) |
| 4–6 | 245 (34.5) |
| 7–9 | 122 (17.2) |
| 10–12 | 46 (6.5) |
| 13–15 | 15 (2.1) |
| 16–18 | 6 (0.8) |
| >19 | 7 (1.0) |
| Unknown | 69 (9.7) |
| Fever | 690 (97.0) |
| Shock | 19 (2.7) |
| Prior surgery | 77 (10.8) |
| Prior nonsurgical invasive procedure | 81 (11.4) |
| Urinary catheter | 133 (18.7) |
| Cirrhosis | 102 (14.3) |
| Diabetes | 163 (22.9) |
| Pulmonary disease | 57 (8.0) |
| HIV infection | 23 (3.2) |
| Chronic kidney disease | 67 (9.4) |
| Cardiac disease | 249 (35.0) |
| Hematological malignancy | 53 (7.5) |
| Solid organ malignancy | 112 (15.8) |
| Neutropenia | 14 (2.0) |
| Solid organ transplant | 32 (4.5) |
| Corticosteroid therapy | 129 (18.1) |
| McCabe, ultimately or rapidly fatal outcome | 278 (39.1) |
| 7-Day mortality | 26 (3.7) |
| 30-Day mortality | 53 (7.5) |
| Persistent bacteremia | 33 (4.6) |
| Correct empirical treatment | 386 (54.3) |
| Prior antibiotic treatment | 169 (23.8) |
| Microbial etiology | |
| Gram-positive cocci | 533 (75.0) |
| Staphylococcus aureus | 327 (46.0) |
| Coagulase-negative staphylococci | 178 (25.0) |
| Enterococcus spp. | 26 (3.7) |
| Gram-negative bacilli | 162 (22.8) |
| Klebsiella spp. | 40 (5.6) |
| Pseudomonas aeruginosa | 32 (4.5) |
| Escherichia coli | 29 (4.1) |
| Enterobacter spp. | 28 (3.9) |
| Serratia spp. | 5 (0.7) |
| Acinetobacter spp. | 5 (0.7) |
| Candida spp. | 9 (1.3) |
a
Values are given as number of patients (percentage) unless otherwise indicated.