TABLE 2.
Relative colony radius of C. dubliniensis strains grown on farnesol-containing YPD agara
| Strainb | Vehicle | [FOH] (μM) |
|||
|---|---|---|---|---|---|
| 25 | 50 | 100 | 200 | ||
| CD36 (I; cdr1756stop/cdr1756stop) | ++++ | +++ | ++ | NG | NG |
| CD38 (I; cdr1756stop/cdr1756stop) | ++++ | ++ | + | NG | NG |
| Wü284 (I; cdr1756stop/cdr1756stop) | ++++ | ++ | NG | NG | NG |
| Wü284 cdr1Δ/Δ | ++++ | ++ | NG | NG | NG |
| CD57 (I; CDR1/CDR1) | ++++ | +++ | +++ | +++ | +++ |
| CD57 cdr1Δ/Δ | ++++ | ++ | ++ | ++ | ++ |
| CD57 tac1Δ/Δ | ++++ | +++ | +++ | +++ | +++ |
| CD57 tac1Δ/Δ znc1Δ/Δ | ++++ | +++ | +++ | +++ | +++ |
| CM1 (I; CDR1/CDR1) | ++++ | +++ | +++ | +++ | +++ |
| CBS8500 (I; CDR1/CDR1) | ++++ | +++ | +++ | +++ | +++ |
| CD506 (II; CDR1/CDR1) | ++++ | ++ | ++ | ++ | +++ |
| CAN6 (II; CDR1/CDR1) | ++++ | +++ | +++ | +++ | +++ |
| p7718 (IV; CDR1/CDR1) | ++++ | +++ | +++ | +++ | +++ |
a
The average radius of colonies formed by each wild-type C. dubliniensis isolate on non-FOH-containing plates (vehicle) was set to 100% to normalize its colony size or its derivative mutants colony size under each growth condition. Data were symbolized by the following transformation: 90 to 110%, ++++; 70 to 90%, +++; 50 to 70%, ++; 30 to 50%, +. NG, no visible colony formation was seen after 40 h of incubation at 30°C.
b
The genotype group (I, II, or IV) of each C. dubliniensis isolate and the presence or absence of the cdr1756stop allele are denoted in parentheses. The genotype of each mutant tested in this table is described in detail in Table S2.