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IC50 values, CC50 values, and selectivity indexes for the effect of K22 treatment on hepacivirus and pestivirus replication and infectivity
| Virus | IC50 (μM) for: |
SIa | CC50 (μM) for: |
||
|---|---|---|---|---|---|
| Replication | Infectivity | Proliferation | Cytotoxicity | ||
| HCV | 7.0 | 2.2 | 9.7 | 21.3 | |
| BVDV SuwaCp | 15.5 | 14.2 | >24.6 | >350 | >1,000 |
| BVDV SuwaNcp | 34.7 | 21.4 | >16.4 | >350 | >1,000 |
SI, selectivity index.
