TABLE 2.

Potency of quinoline inhibitors in the presence of serum^a

Compound	MIC against E. coli CFT073 ΔtolC (μg/ml)
	No serum	10% mouse serum
G592	18 ± 5	>41
G913	<0.22 ± 0.15	5.6 ± 3.9
G332	0.31 ± 0.22	4.2 ± 1.6

^aFor all samples, n ≥ 3. The plasma protein binding level for all compounds was 99%.