Table 4.

Outcomes.

Outcomes	Control n=51	GDT n=48	p-value
Primary outcomes
Scr difference 8h	0.10 [0.00-0.37]	0.10 [-0.10-0.40]	0.482
Scr difference day 1	0.00 [-0.10-0.30]	0.10 [-0.20-0.60]	0.960
Scr difference day 2	0.10 [-0.14-0.60]	0.17 [-0.25-0.80]	0.768
Scr difference day 3	0.10 [-0.30-0.54]	0.10 [-0.35-0.70]	0.914
RRT, n (%)	12 (25.0)	13 (27.1)	0.818
8-h diuresis, ml	396.5 [200.0-500.0]	397.5 [252.5-537.5]	0.515
AKI beyond 72h, n (%)	40 (78.4)	30 (62.5)	0.064
Secondary outcomes
ICU LOS, days	7.5 [4.0-14.0]	7.0 [5.0-13.0]	0.579
Hospital LOS, days	15.0 [10.0-25.5]	18.5 [10.0-27.0]	0.745
ICU mortality, n (%)	15 (29.4)	10 (20.8)	0.326
Hospital mortality, n (%)	26 (51.0)	15 (31.3)	0.048
Composite, n (%)	44 (86.3)	37 (77.1)	0.178

SCr difference: Difference in serum creatinine level (8h and 1, 2, and 3 days after minus before initiation of goal-directed therapy). Composite: composite of hospital mortality, renal replacement therapy, or persistent renal functional impairment after 72h. Numbers are presented as n (%) or the median [IQR].