Figure 2.

Overexpression of LINC00312 suppressed CRC cell proliferation, migration and invasion in vitro. A, SW620 and LoVo cells were infected with a LINC00312‐carrying lentivirus (Lv‐LINC00312) and a control lentivirus (Lv‐control), and qRT‐PCR was conducted to measure LINC00312 expression. B, Cell proliferation assay (CCK‐8). C, Flow‐cytometric analysis of the cell cycle distribution. D, Representative pictures (top) and quantification (bottom) of EdU‐positive cells. E, Transwell assay was performed to investigate changes in cell migration and invasiveness. Representative images (left) and quantification (right) are also shown. Data are presented as mean ± SD. *P < 0.05, **P < 0.01