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. 2018 Sep 7;3(1):149–163. doi: 10.20411/pai.v3i1.242

Figure 1.

Figure 1.

Normalization of clinical parameters over the course of IFN-free DAA therapy. A) Plasma HCV viral level is not detectable (lower limit of detection 15 IU/ml) at week 4 after starting DAA therapy. Log10 HCV viral level is shown over time after start of HCV DAA therapy at week 0 (w0). B) TE score (significantly decreases at week 24 after completion of DAA therapy SVR24 (P = 0.024). C) Albumin level over course of therapy in HCV-infected cohort as well as at 1 time point in uninfected donors (UD). Red dotted line indicates lower limit of normal. D) AST level over course of therapy in HCV-infected cohort (W0, W4, W8, and W20-24) as well as at 1 time point in uninfected donors (UD). Red dotted line indicates upper limit of normal. E) ALT level over course of therapy in HCV-infected cohort as well as at 1 time point in uninfected donors (UD). Red dotted line indicates upper limit of normal. F) PLT level over course of therapy in HCV-infected cohort as well as at 1 time point in uninfected donors. Red dotted line indicates lower limit of normal.