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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Trends Pharmacol Sci. 2018 Nov;39(11):953–966. doi: 10.1016/j.tips.2018.08.006

Figure 1. LPL receptor ligands, proteins, human and mouse genes, and historic names.

Figure 1

(A) Structures of the major S1PR and LPAR ligands referred to in the text are shown on the left of their respective receptor families. Lipid nomenclature (e.g., 18:1) is described in greater detail in the glossary. (B) Protein Data Bank (PDB) accession numbers for crystal structures used in figures in this text are shown in bold and species of receptor crystallized (human, Homo sapiens (h), or zebrafish, Danio rerio (d)) is given in parenthesis, followed by rhodopsin receptor subclass and family (EDG versus P2Y), current human and mouse gene names, and major historic names for each LPL receptor. aGPCR26 should not be confused with GPR26, which is incorrectly given as a synonym for LPAR1 in NCBI, Ensembl, and other databases. The mouse listings for Lparl correctly list only Gpcr26. 2-ALPA, 2-arachidonylphosphatidic acid; AGP, alkylglycerol 3-phosphate; dhS1P, dihydrosphingosine 1-phosphate (also referred to as sphinganine 1-phosphate); LPA, lysophosphatidic acid.