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. 2018 Aug 30;22(11):5720–5731. doi: 10.1111/jcmm.13848

Figure 8.

Figure 8

Schematics of mechanism of PD on IVDD. PD treatment suppresses Keap1 and enhances Nrf2 to activate Nrf2/HO‐1 signalling pathway to scavenge TNF‐α‐induced ROS, rescuing senescence and excessive ECM destruction in NPCs