Table 1.

Rat foot swelling (mm).

Time (d)	Normal	Model	TG	ISM-H	ISM-L	ISM-T
−1	4.73 ± 1.08	l4.79 ± 0.43	4.81 ± 0.79	4.74 ± 0.65	4.68 ± 0.51	4.85 ± 0.64
3	5.02 ± 1.26∗∗	7.47 ± 2.45∗∗	7.58 ± 2.56∗∗	7.63 ± 2.61∗∗	7.50 ± 2.48∗∗	7.66 ± 2.65∗∗
7	5.22 ± 1.18∗∗	7.50 ± 0.08	7.69 ± 1.38	7.50 ± 1.34	7.45 ± 0.68	7.74 ± 1.07
11	5.52 ± 0.89∗∗	7.88 ± 1.53	7.76 ± 1.05	7.81 ± 0.98	8.01 ± 1.08	7.91 ± 1.28
15	5.78 ± 0.58∗∗	7.82 ± 1.19	7.69 ± 1.09	7.70 ± 0.68	7.75 ± 1.05	7.69 ± 1.08
19	6.03 ± 0.74∗∗	7.65 ± 1.08	6.89 ± 0.98	7.03 ± 0.91∗	7.09 ± 0.87∗	7.50 ± 1.02
23	6.15 ± 1.02∗∗	7.41 ± 1.01	6.36 ± 0.75∗∗	6.81 ± 0.78∗∗#	7.06 ± 1.01∗##	7.20 ± 0.88#
27	6.28 ± 1.19∗∗	7.15 ± 1.57	6.21 ± 0.88∗∗	6.55 ± 0.58∗∗	6.35 ± 0.73∗∗	6.66 ± 0.62∗

Note: ^∗p < 0.05, ^∗∗p < 0.01, vs model group; ^#p < 0.05, ^##p < 0.01, vs TG group.