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. 2018 Aug 8;7(16):e007459. doi: 10.1161/JAHA.117.007459

Table 2.

Percentage of the Association Between Each Physical Activity Parameter and Each Biomarker That Is Mediated by Fat Mass Index in Men and Women: Path Analysis

PAEE MVPA LPA SED
CRP
Men 38.8 38.3 37.1 39.2
Women 50.6 49.8 57.7 54.5
IL‐6
Men 22.7 20.9 35.0 26.7
Women 40.6 39.7 46.5 43.4
t‐PA
Men 26.0 67.4 8.4 16.0
Women 52.3 49.3 57.7 54.3
E‐selectin
Men 55.9 84.5 18.5 40.7
Women 76.0 77.8 84.1 82.1
Leptin
Men 59.4 58.0 64.9 61.3
Women 67.7 63.3 71.7 69.1
Adiponectin
Men 52.0 64.5 21.4 34.4
Women 54.3 92.7 38.6 43.8

Data show % of the total effects of each activity parameter that is mediated by fat mass index (indirect effect through fat mass/total effect). Adjusted for age, SEP, smoking history, long‐term illness, health problem or disability, blood pressure, cardiovascular disease, and medication use. CRP indicates C‐reactive protein; IL‐6, interleukin‐6; LPA, light‐intensity physical activity; MVPA, moderate‐to‐vigorous physical activity; PAEE, physical activity energy expenditure; SED, sedentary; SEP, socioeconomic position; t‐PA, tissue‐plasminogen activator.