Table 1.
Association Between CEC and Prevalent CAD Case‐Control Status in the MHI Biobank Phase 1 (943 Controls and 954 CAD Cases)
| CEC | Baseline Model | Adjusted for HDL‐C and Triglycerides | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | |
| J774 basal | 0.62 | 0.56–0.69 | <2.2×10−16 | 0.63 | 0.54–0.72 | 4.1×10−11 |
| J774 stimulated | 0.65 | 0.58–0.72 | <2.2×10−16 | 0.73 | 0.65–0.83 | 1.4×10−6 |
| J774 ABCA1 dependent | 0.85 | 0.77–0.94 | 0.0012 | 0.94 | 0.84–1.05 | 0.29 |
| BHK stimulated | 0.90 | 0.81–1.00 | 0.039 | 1.23 | 1.08–1.40 | 0.0015 |
The ORs and 95% CIs are provided per SD of CEC. All models are adjusted for sex, age squared, and statin use. When indicated, we also adjusted for HDL‐C and triglyceride levels. BHK indicates baby hamster kidney; CAD, coronary artery disease; CEC, cholesterol efflux capacity; CI, confidence interval; HDL‐C, high‐density lipoprotein cholesterol; MHI, Montreal Heart Institute; OR, odds ratio.