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. 2018 Aug 15;7(16):e009012. doi: 10.1161/JAHA.118.009012

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Relative risks for cardiovascular outcomes in individuals in the top vs bottom tertile of osteoprotegerin (OPG) concentration, according to categories of study‐level characteristics. *P values were calculated from meta‐regression. Levels of adjustment: o, unadjusted; ++, adjusted for age, sex, and non–blood‐based risk factors; +++, additionally adjusted for at least 1 blood‐based risk factor. ACS indicates acute coronary syndrome; CI, confidence interval; IFMA, immunofluorometric assay.