Table 1.
Fold Changes and P Values of Differentially Regulated Genes Following Treatment With Either sCD74/rMIF, rMIF, or sCD74
| sCD74/rMIF vs Control | rMIF vs Control | sCD74 vs Control | ||||||
|---|---|---|---|---|---|---|---|---|
| Gene Symbol | FC | P Value | Gene Symbol | FC | P Value | Gene Symbol | FC | P Value |
| Gm20917 | −2.02 | 0.0373 | Ddb2 | −1.9 | 0.0342 | Zfp616 | −2.36 | 0.0211 |
| Dsg1b | −1.9 | 0.0246 | Gm11099 | −1.82 | 0.0113 | Olfr830 | −1.67 | 0.0422 |
| Olfr77 | −1.72 | 0.0369 | Gjb6 | −1.69 | 0.0351 | Ceacam14 | −1.64 | 0.0416 |
| Akr1c12 | −1.69 | 0.0090 | Olfr74 | −1.69 | 0.0495 | Gm10735 | −1.6 | 0.0021 |
| LOC105242925 | −1.69 | 0.0263 | Ceacam13 | −1.67 | 0.0342 | Serpinb9e | −1.53 | 0.0216 |
| Afm | −1.65 | 0.0072 | Sel1 l2 | −1.66 | 0.0011 | Bpifa5 | −1.52 | 0.0254 |
| Cfap53 | −1.59 | 0.0351 | Tspan1 | −1.66 | 0.0122 | Mfap2 | −1.52 | 0.0400 |
| Pja1 | −1.58 | 0.0191 | Rs1 | −1.65 | 0.0362 | Gm13304 | −1.5 | 0.0126 |
| Ctsm | −1.56 | 0.0307 | LOC102637808 | −1.63 | 0.0205 | 1810064F22Rik | −1.5 | 0.0495 |
| Nrxn3 | −1.55 | 0.0075 | Pabpc4 l | −1.63 | 0.0420 | Kcnj10 | −1.5 | 0.0499 |
| Mmp1b | −1.55 | 0.0137 | Smr3a | −1.63 | 0.0458 | Zscan30 | 1.5 | 0.0095 |
| Vmn2r89 | −1.55 | 0.0282 | Myrip | −1.62 | 0.0180 | Olfr1184 | 1.58 | 0.0190 |
| Tnnt3 | −1.53 | 0.0181 | LOC105242925 | −1.61 | 0.0328 | Vmn2r74 | 1.71 | 0.0198 |
| Serpinb13 | −1.53 | 0.0416 | Srsx | −1.6 | 0.0289 | Gm8050 | 1.81 | 0.0283 |
| Gjb6 | −1.52 | 0.0169 | Vmn2r46 | −1.6 | 0.0309 | |||
| Hgd | −1.51 | 0.0335 | Vmn1r222 | −1.55 | 0.0145 | |||
| Nfkbia | 1.5 | 0.0077 | Gm14151 | −1.54 | 0.0074 | |||
| Scgb2b23‐ps | 1.5 | 0.0194 | Vmn1r180 | −1.53 | 0.0126 | |||
| Gpr176 | 1.5 | 0.0198 | Bcl2 l15 | −1.52 | 0.0192 | |||
| Tnip1 | 1.5 | 0.0384 | Akr1c12 | −1.5 | 0.0170 | |||
| Alg3 | 1.51 | 0.0417 | Pnmal2 | −1.5 | 0.0233 | |||
| Unc13c | 1.52 | 0.0271 | Fga | 1.5 | 0.0040 | |||
| Ripk2 | 1.52 | 0.0312 | Ets2 | 1.5 | 0.0169 | |||
| Clmn | 1.52 | 0.0490 | Serpina3 g | 1.5 | 0.0336 | |||
| Serpinf1 | 1.53 | 0.0137 | Gm5155 | 1.51 | 0.0258 | |||
| Phlda1 | 1.55 | 0.0087 | Gm8267 | 1.52 | 0.0097 | |||
| Samt2 | 1.56 | 0.0030 | 1700015F17Rik | 1.53 | 0.0028 | |||
| Ren1 | 1.59 | 0.0008 | Dnah8 | 1.53 | 0.0381 | |||
| Tdrp | 1.59 | 0.0038 | E130114P18Rik | 1.54 | 0.0150 | |||
| E130114P18Rik | 1.59 | 0.0230 | Rhox4f | 1.54 | 0.0461 | |||
| Adam18 | 1.59 | 0.0266 | Zc2hc1b | 1.55 | 0.0044 | |||
| Ptgir | 1.6 | 0.0172 | Vmn1r62 | 1.57 | 0.0262 | |||
| Tnfsf18 | 1.61 | 0.0164 | Vmn1r62 | 1.57 | 0.0262 | |||
| Tpgs1 | 1.61 | 0.0367 | Slc22a18 | 1.57 | 0.0417 | |||
| Mrpl38 | 1.63 | 0.0148 | Vmn1r228 | 1.6 | 0.0038 | |||
| Olfr1129 | 1.64 | 0.0060 | Slco3a1 | 1.6 | 0.0193 | |||
| Eif6 | 1.64 | 0.0302 | Meiob | 1.64 | 0.0315 | |||
| Slc7a2 | 1.65 | 0.0022 | Olfr1129 | 1.65 | 0.0099 | |||
| Gm21907 | 1.71 | 0.0218 | Mmp13 | 1.66 | 0.0245 | |||
| Marco | 1.73 | 0.0110 | Hoxa13 | 1.67 | 0.0468 | |||
| Cyp2j12 | 1.8 | 0.0300 | Vmn1r28 | 1.71 | 0.0257 | |||
| Isg20 | 1.81 | 0.0085 | Slc7a2 | 1.78 | 0.0325 | |||
| Iigp1 | 1.81 | 0.0318 | Ddx43 | 1.79 | 0.0217 | |||
| Ltbp2 | 1.82 | 0.0081 | Ren1 | 1.88 | 0.0059 | |||
| Pydc3 | 1.85 | 0.0472 | Ifi44 | 1.94 | 0.0419 | |||
| Birc3 | 1.87 | 0.0166 | Gm11096 | 30.61 | 0.0002 | |||
| Mapk11 | 2.06 | 0.0351 | ||||||
| Slco3a1 | 2.08 | 0.0108 | ||||||
| Ccl7 | 2.19 | 0.0005 | ||||||
| Oasl2 | 2.73 | 0.0316 | ||||||
| Ccl2 | 2.9 | 0.0191 | ||||||
| Tgtp2 | 3.12 | 0.0223 | ||||||
| Clec4e | 3.82 | 0.0234 | ||||||
| Irg1 | 4.77 | 0.0073 | ||||||
| Ifi44 | 5.22 | 0.0203 | ||||||
FC indicates fold change; rMIF, recombinant macrophage migration inhibitory factor; sCD74, soluble CD74.