Table 1.
Demographic, Laboratory, and Clinical Characteristics of Study Patients Stratified by Presence or Absence of Microvascular Endothelial Dysfunction and by Presence or Absence of Epicardial Endothelial Dysfunction
| All Patients (n=79) | Normal Microvascular Endothelial Function 30 (38%) | Microvascular Endothelial Dysfunction 49 (62%) | Normal Epicardial Endothelial Function 58 (74%) | Epicardial Endothelial Dysfunction 20 (26%) | |
|---|---|---|---|---|---|
| Age, y | 53±10 | 51±10 | 54±11 | 51±10 | 57±9a |
| Sex (women) | 59 (75) | 23 (39) | 36 (61) | 44 (76) | 14 (24) |
| Body mass index, kg/m2 | 30±7 | 30±7 | 31±7 | 31±7 | 29±5 |
| Baseline mean arterial pressure, mm Hg | 99±14 | 100±10 | 99±16 | 101±13 | 95±15 |
| Baseline heart rate, beats per minute | 73±17 | 71±14 | 74±19 | 75±17 | 67±15 |
| Total cholesterol, mg/dL | 189±45 | 198±45 | 184±45 | 186±45 | 198±46 |
| Triglycerides, mg/dL | 130±79 | 151±102 | 117±59 | 135±82 | 117±73 |
| High‐density lipoprotein, mg/dL | 60±19 | 58±19 | 61±19 | 57±18 | 67±21 |
| Low‐density lipoprotein, mg/dL | 104±39 | 112±36 | 100±40 | 103±37 | 109±44 |
| Serum CRP, mg/L | 3.96±5.58 | 4.40±7.43 | 3.68±4.02 | 4.12±6.01 | 3.36±4.51 |
| Diabetes mellitus | 2 (3) | 1 (50) | 1 (50) | 2 (100) | 0 |
| Hypertension | 39 (50) | 15 (38) | 24 (62) | 29 (74) | 9 (26) |
| Hyperlipidemia | 49 (64) | 20 (41) | 29 (59) | 36 (73) | 13 (27) |
| Tobacco smoking | 26 (35) | 10 (38) | 16 (62) | 17 (65) | 9 (35) |
Numbers are mean±SD or proportions with n (%). CRP indicates C‐reactive protein.
a
P<0.05 vs normal epicardial endothelial function.