Table 1.
Baseline Characteristics
| Characteristics | Value (n=288) |
|---|---|
| Clinical parameters | |
| Age, y | 80.7±5.3 |
| BMI, kg/m2 | 26.7±5.3 |
| Female sex, n (%) | 168 (58.3) |
| Hypertension, n (%) | 248 (86.1) |
| Diabetes mellitus, n (%) | 76 (26.4) |
| Dyslipidemia, n (%) | 153 (53.1) |
| Prior acute heart failure, n (%) | 109 (37.8) |
| Prior myocardial infarction, n (%) | 53 (18.4) |
| Prior stroke, n (%) | 18 (6.3) |
| Prior TIA, n (%) | 21 (7.3) |
| Prior bypass graft surgery, n (%) | 31 (10.8) |
| Prior percutaneous coronary intervention, n (%) | 88 (30.6) |
| Peripheral vascular disease, n (%) | 17 (5.9) |
| Chronic obstructive pulmonary disease, n (%) | 102 (35.4) |
| Cirrhosis, n (%) | 8 (2.8) |
| Renal insufficiencya, n (%)* | 59 (20.5) |
| Atrial fibrillation, n (%) | 44 (15.3) |
| Prior pacemaker, n (%) | 28 (9.7) |
| NYHA class III and IV, n (%) | 195 (67.7) |
| STS score, % | 8.1±5.1 |
| Baseline echocardiographic parameters | |
| Left ventricular ejection fraction, % | 51.5±10.5 |
| Peak pressure gradient, mm Hg | 86.2±24.4 |
| Mean pressure gradient, mm Hg | 53.3±15.9 |
| Aortic valve area, cm2 | 0.5±0.3 |
Data are given as mean±SD unless otherwise indicated. BMI indicates body mass index; NYHA, New York Heart Association; STS, Society of Thoracic Surgery; and TIA, transient ischemic attack.
a
Glomerular filtration rate, <30 mL/min.