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Proteinuria, renal blood flow (RBF), and sodium reabsorption efficiency (TNa/QO 2) after 2 weeks of nitric oxide synthase (NOS) inhibition (n=21) compared with controls (n=7). Proteinuria was measured from urine collected in metabolic cages for 24 hours. Hemodynamics were measured under isoflurane anesthesia. ***P≤0.001 vs control, unpaired Student t test.
