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. 2018 Oct 24;13:210. doi: 10.1186/s13014-018-1153-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Effect of HIF-1α knockdown on the cell viability and apoptosis of HeLa and C33A cell exposed to radiation. HeLa and C33A cells were divided into six groups: control, radiation, radiation+Ad-GFP, radiation+Ad-HOTAIR, radiation+Ad-HOTAIR + si-NC, and radiation+Ad-HOTAIR + si-HIF-1α groups. The cell viability (a) and apoptosis (b) of HeLa and C33A cell exposed to radiation were examined. The data are represented as mean ± SD. **vs control cells, P < 0.01; ##vs cells irradiated with a dose of 2 Gy and transfected with Ad-GFP, P < 0.01; &vs cells irradiated with a dose of 2 Gy and transfected with Ad-HOTAIR and si-NC (scrambled sequence), P < 0.01. All the experiment performed in triplicate