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. 2018 Oct 17;24:7414–7423. doi: 10.12659/MSM.910738

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© Med Sci Monit, 2018

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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Photomicrographs of the immunohistochemical staining of aldo-keto reductase family 1 member B10 (AKR1B10) showing cytoplasmic immunoreactivity in hepatocellular carcinoma (HCC) tissue and liver cirrhosis tissue. (A) Well-differentiated HCC tissue stained for AKR1B10 using immunohistochemistry shows cytoplasmic immunostaining. A significant increase in AKR1B10 immunostaining of the cytoplasm is seen. Original magnification ×200. (B) Moderately-differentiated HCC tissue stained for AKR1B10 using immunohistochemistry. Original magnification ×200. (C) Poorly-differentiated HCC tissue stained for AKR1B10 using immunohistochemistry. Original magnification ×200. (D) Liver cirrhosis tissue stained for AKR1B10 using immunohistochemistry. Original magnification ×200.