Table 1:
Summary of key model parameters over a 4-month period
| Variable/state | Value (range) | Source |
|---|---|---|
| Transition probability, % | ||
| Rate of development of low-risk diabetic foot ulcer | 0.3 (0.3–0.41) | Lavery et al.39 |
| Rate of development of moderate-risk diabetic foot ulcer | 0.45 (0.45–2.18) | Lavery et al.39 |
| Rate of development of recurrent diabetic foot ulcer | 11.21 (7.17–15.66) | Armstrong et al.,40 Dubský et al.41 |
| Healing rate for low-risk diabetic foot ulcer | 45.71 | Prompers et al.42 |
| Healing rate for moderate-risk diabetic foot ulcer | 32.32 | Prompers et al.42 |
| Healing rate for recurrent diabetic foot ulcer | 11.51 | Örneholm et al.43 |
| Amputation rate for low-risk diabetic foot ulcer | 0.67 (0.3–0.77) | Lavery et al.,39 Prompers et al.,42 Moulik et al.44 |
| Amputation rate for moderate-risk diabetic foot ulcer | 2.74 (0.063–8.54) | Lavery et al.,39 Prompers et al.,42 Morbach et al.,45 Oyibo et al.46 |
| Amputation rate for recurrent diabetic foot ulcer | 3.45 (0.68–3.45) | Lavery et al.,39 Örneholm et al.43 |
| Mortality rate for low-risk diabetic foot ulcer | 1.17 (1.01–2.73) | Prompers et al.,42 Morbach et al.45 |
| Mortality rate for moderate-risk diabetic foot ulcer | 3.26 (3.26–8.07) | Prompers et al.,42 Morbach et al.45 |
| Mortality rate for recurrent diabetic foot ulcer | 3.26 (3.26–8.07) | Prompers et al.,42 Örneholm et al.,43 Morbach et al.45 |
| Mortality rate for amputation | See Supplementary Figure A3, Appendix 1 | Aulivola et al.47 |
| Utility/cost* | ||
| No ulcer | 0.7850 (0.681–0.889) | Beaudet et al.48 |
| Active diabetic foot ulcer | 0.615 (0.578–0.652) | Beaudet et al.48 |
| Healed diabetic foot ulcer | 0.680 | Redekop et al.49 |
| Amputation | 0.505 (0.396–0.615) | Beaudet et al.48 |
| Initial screen, $ | 60.00 | Ontario Ministry of Health and Long-Term Care50 |
| At low risk for diabetic foot ulcer, $ | 67.80 | Ontario Ministry of Health and Long-Term Care50 |
| At moderate risk for diabetic foot ulcer, $ | 85.87 | Ontario Ministry of Health and Long-Term Care50 |
| Diabetic foot ulcer, $ | 2395.75 | Ontario Ministry of Health and Long-Term Care,50 Canadian Institute for Health Information51 |
| Amputation, $ | 16 752.15 | Ontario Ministry of Health and Long-Term Care,50 Canadian Institute for Health Information51 |
| Healed amputation, $ | 78.40 | Ontario Ministry of Health and Long-Term Care,50 Canadian Institute for Health Information51 |
| Healed diabetic foot ulcer, $ | 135.60 | Ontario Ministry of Health and Long-Term Care50 |
| Telemedicine device, $ | 20.00 | Fasterholdt et al.52 |
| Telemedicine service, $ | 14.65 | Ontario Telemedicine Network53 |
*
2015 Canadian dollars.