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. 2018 Oct 23;8(1):1533754. doi: 10.1080/20010001.2018.1533754

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Glomerulonephritis, inflammation, and disease burden in Tg(TXN)^+/0 and WT mice. The severity of glomerulonephritis (Figure 5(a): left), and inflammation (Figure 5(b): center), and total number of pathological changes (disease burden: Figure 5(c): right) were determined in Tg(TXN)^+/0 (closed bar) and WT (open bar) mice (22–25 months old). The cohort consists of 38 Tg(TXN)^+/0 mice and 48 WT male mice. The disease burden in Tg(TXN)^+/0 mice was similar to WT mice. No significant changes were found in the severity of glomerulonephritis or inflammation in Tg(TXN)^+/0 mice compared to WT mice.