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. 2018 Oct 23;8(1):1533754. doi: 10.1080/20010001.2018.1533754

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Levels of total ASK1 and phosphorylated ASK1 in Tg(TXN)^+/0 and WT mice. The levels of ASK1 and phosphorylated ASK1 were measured in the livers of young (6–7 months old: Figure 7(a,b)) and old (22–24 months old: Figure 7(c,d)) Tg(TXN)^+/0 (closed bar) and WT (open bar) mice by Western blot analysis. The levels of ASK1 (Figure 7(a,c)) were similar between Tg(TXN)^+/0 and WT mice. However, phosphorylated ASK1 levels (Figure 7(b,d)) were significantly lower in young and old Tg(TXN)^+/0 compared to WT mice (*p < 0.05). The data are the mean ± SEM from three to five mice.