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. 2018 Oct 23;8(1):1533754. doi: 10.1080/20010001.2018.1533754

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Cytochrome c release, caspase-3 activity, and bcl-2 levels in Tg(TXN)^+/0 and WT mice. Cytochrome c release (Figure 8(a): left), caspase-3 activity (Figure 8(b): center), and bcl-2 levels (Figure 8(c): right) were measured by Western blot analysis to assess the mitochondrial apoptosis pathway in the livers of 6 to 7 month old Tg(TXN)^+/0 (closed bar) and WT (open bar) mice. Cytochrome c release, caspase-3 activity, and bcl-2 levels were similar between Tg(TXN)^+/0 and WT mice. The values are the mean ± SEM of five mice per group.