Table 7.
Characteristics of studies included in meta-analysis.
| Variant | References | Ethnicity | PMID | DM | Trait | N | Selection criteria | N | Selection criteria | N | Selection criteria | HWE HT | HWE DC | Analyses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SLC2A1 rs841853 | [10] | Caucasians | 19822956 | T2DM | DN | 92 | Pers. albuminuria | 56 | DM >15 y, pers. norm/ria matched for age, BMI | 92 | Non-diabetics matched for age, BMI | No | DC-C, HT-DC-C, HT-C | |
| [36] | Africans (Tunisia) | 18821326 | T2DM | DN | 126 | Pers. albuminuria, retinopathy | 273 | DM >10 y, norm/ria | No | DC-C | ||||
| [37] | Caucasians | 12086959 | T1DM | DN | 262 | Pers. macr/ria or d. ESRD | 230 | Pers. norm/ria , DM ≥15 y | DC-C | |||||
| [38] | Caucasians | 11231353 | T1DM | DN | 70 | Pers. proteinuria, retinopathy, DM ≥10 y | 44 | DM≥ 20 y, pers. norm/ria | 104 | Non-diabetics | DC-C, HT-DC-C, HT-C | |||
| [39] | Caucasians | 11477169 | T1DM | DN | 199 | Pers. macr/ria , retinopathy | 192 | Pers. norm/ria matched for gender, age, DM duration | DC-C | |||||
| [40] | E. Asians | 10231446 | T2DM | DN | 64 | Pers. albuminuria or proteinuria with or without impaired renal function | 45 | Only diabetics | 124 | Non-diabetics | DC-C, HT-DC-C, HT-C | |||
| [41] | Caucasians | 11168944 | T2DM | DN | 282 | Pers. micr/ria/proteinuria/CRF | 162 | Pers. norm/ria, DM ≥10 y | 194 | Non-diabetics | No | DC-C, HT-DC-C, HT-C | ||
| [42] | Caucasians | 9789717 | T2DM | DN | 60 | Pers. micro/macroalbuminuria | 100 | Pers. norm/ria matched for gender, age, BMI, DM duration and HbA1c and lipidic profile | 90 | Non-diabetics | DC-C, HT-DC-C, HT-C | |||
| SLC2A1 rs1385129 | [43] | Caucasians-Brazilians | 25701507 | T1DM | DN | 203 | Pers. micro/macroalbuminuria | 249 | Pers. norm/ria and serum Cr.<1.7 mg/dl | DC-C | ||||
| [44] | Asians | 26337659 | T2DM | DN | 126 | Pers. micr/ria | 150 | Pers. norm/ria | No | DC-C | ||||
| [36] | Africans (Tunisia) | 18821326 | T2DM | DN | 126 | Pers. albuminuria, retinopathy | 273 | DM >10 y, norm/ria | DC-C | |||||
| [37] | Caucasians | 12086959 | T1DM | DN | 262 | Pers. macr/ria or d. ESRD | 230 | Pers. norm/ria , DM duration ≥15 y | DC-C | |||||
| SLC2A1 rs841847 | [36] | Africans (Tunisia) | 18821326 | T2DM | DN | 126 | Pers. albuminuria, retinopathy | 273 | DM >10 y, norm/ria | DC-C | ||||
| [43] | Caucasians-Brazilians | 25701507 | T1DM | DN | 203 | Pers. micro/macroalbuminuria | 249 | Pers. norm/ria and serum Cr.<1.7 mg/dl | DC-C | |||||
| [37] | Caucasians | 12086959 | T1DM | DN | 262 | Pers. macr/ria or d. ESRD | 230 | Pers. norm/ria, DM ≥15 y | DC-C | |||||
| SLC2A1 rs841848 | [36] | Africans (Tunisia) | 18821326 | T2DM | DN | 126 | Pers. albuminuria, retinopathy | 273 | DM >10 y, norm/ria | DC-C | ||||
| [43] | Caucasians-Brazilians | 25701507 | T1DM | DN | 203 | Pers. micro/macroalbuminuria | 249 | Pers. norm/ria and s. Cr.<1.7 mg/dl | DC-C | |||||
| [37] | Caucasians | 12086959 | T1DM | DN | 262 | Pers. macr/ria or d. ESRD | 230 | Pers. norm/ria , DM ≥15 y | DC-C | |||||
| SLC2A1 rs710218 | [36] | Africans (Tunisia) | 18821326 | T2DM | DN | 126 | Pers. albuminuria, retinopathy | 273 | DM >10 y, norm/ria | No | DC-C | |||
| [38] | Caucasians | 15745834 | T1DM | DN | 131 | DM ≥10 y, pers. proteinuria, diabetic retinopathy | 72 | Uncomplicated, DM ≥20 y without retinopathy and proteinuria | 99 | Non-diabetics | DC-C | |||
| 35 | DM <10 y without retinopathy, proteinuria or overt neuropathy |