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. 2018 Sep 27;9:574. doi: 10.3389/fendo.2018.00574

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Copyright © 2018 Liu, He, Ning, Luo, Li, Zhang, Chen and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DIO Nile tilapia with LR presented selective regulation of leptin in lipid or glucose metabolism. (A) NtrelepA administration effects on glucose tolerance test (n = 5). (B–D) NtrelepA administration effects on plasma glucose, TG and NEFA levels (n = 6). (E) ATGL and apoE mRNA in liver (n = 6). (F) Glut2 mRNA in liver (n = 6). (G) FPKM of Glut2, ATGL, and apoE in liver. (H–K) Gene expression analysis 2 h after NtrelepA administration (n = 6). ATGL mRNA levels in liver (H). LPL and CPT1a mRNA levels in liver (I,J). Glut2 mRNA levels in liver (K). ^*p < 0.05 and ^**p < 0.01. Data shown as means ± SEM.