Figure 3. Ad hoc semiquantitative scoring scheme for CD44v8-10 expression.

Expression of CD44v8-10 on tumor cell membranes was determined using a 0+ to 3+ scale. The histo-score (H-score) for each patient was calculated using the following formula: (% of cells 3+) × 3 + (% of cells 2+) × 2 + (% of cells 1+). H-score ≥ 151 was provisionally defined as high CD44v8-10 expression.