Table 1. Measurements of Relative DTI Metrics in IC, TP, Oligemia and NT as Compared to Contralateral Homologous Normal Brain at Each Time Point (All Numbers in Percentages).
DTI metrics* | 30 Min | 60 Min | 90 Min | 120 Min | 150 Min | 180 Min |
---|---|---|---|---|---|---|
IC | ||||||
rFA | 14.17 ± 1.49 | 13.40 ± 2.19 | 8.66 ± 2.23 | 5.04 ± 2.15 | 1.62 ± 2.16 | −0.90 ± 1.92 |
rq | −24.08 ± 1.14 | −30.46 ± 1.44 | −37.03 ± 1.20 | −40.41 ± 1.60 | −43.64 ± 1.72 | −45.35 ± 1.51 |
rL | −33.21 ± 0.72 | −38.45 ± 1.15 | −41.44 ± 1.38 | −42.66 ± 1.32 | −43.78 ± 1.40 | −44.44 ± 1.17 |
rMD | −33.97 ± 0.73 | −39.20 ± 1.20 | −41.88 ± 1.44 | −42.93 ± 1.36 | −43.94 ± 1.43 | −44.46 ± 1.19 |
rAD | −31.68 ± 0.73 | −37.10 ± 1.11 | −40.76 ± 1.27 | −42.41 ± 1.29 | −43.88 ± 1.39 | −44.82 ± 1.15 |
rRD | −35.80 ± 0.80 | −40.88 ± 1.34 | −42.78 ± 1.62 | −43.34 ± 1.50 | −44.01 ± 1.56 | −44.17 ± 1.32 |
TP | ||||||
rFA | 4.58 ± 1.28 | 10.24 ± 1.90 | 12.32 ± 1.74 | 8.77 ± 1.42 | 6.72 ± 1.49 | 4.73 ± 1.64 |
rq | −6.94 ± 1.39 | −14.20 ± 1.73 | −19.33 ± 2.10 | −26.35 ± 2.03 | −30.60 ± 2.83 | −36.98 ± 2.72 |
rL | −11.37 ± 1.24 | −22.36 ± 1.50 | −28.43 ± 2.04 | −33.00 ± 1.97 | −36.26 ± 2.24 | −40.79 ± 1.83 |
rMD | −11.88 ± 1.31 | −23.17 ± 1.54 | −29.45 ± 2.02 | −33.71 ± 1.96 | −36.95 ± 2.18 | −41.37 ± 1.71 |
rAD | −10.69 ± 1.18 | −20.95 ± 1.45 | −26.82 ± 2.01 | −31.81 ± 1.99 | −35.25 ± 2.35 | −40.20 ± 1.97 |
rRD | −12.88 ± 1.47 | −24.97 ± 1.72 | −31.68 ± 2.07 | −35.34 ± 1.95 | −38.40 ± 2.06 | −42.42 ± 1.50 |
Oligemia | ||||||
rFA | 1.62 ± 1.06 | 3.77 ± 1.66 | 4.79 ± 2.05 | 6.13 ± 1.89 | 4.47 ± 1.58 | 7.56 ± 2.39 |
rq | −0.59 ± 1.23 | 1.31 ± 1.70 | 0.76 ± 1.80 | 1.67 ± 1.78 | −1.26 ± 1.58 | 1.50 ± 1.99 |
rL | −1.25 ± 0.63 | −1.70 ± 0.66 | −3.32 ± 0.81 | −3.04 ± 0.84 | −4.35 ± 0.86 | −4.58 ± 0.86 |
rMD | −1.32 ± 0.62 | −2.01 ± 0.70 | −3.70 ± 0.90 | −3.45 ± 0.90 | −4.62 ± 0.89 | −5.11 ± 0.94 |
rAD | −1.13 ± 0.68 | −1.10 ± 0.62 | −2.52 ± 0.68 | −2.13 ± 0.84 | −3.75 ± 0.92 | −3.35 ± 0.84 |
rRD | −1.46 ± 0.67 | −2.76 ± 0.96 | −4.60 ± 1.20 | −4.45 ± 1.11 | −5.22 ± 0.99 | −6.48 ± 1.24 |
NT | ||||||
rFA | 3.81 ± 0.78 | 4.26 ± 0.87 | 4.88 ± 1.22 | 5.47 ± 1.16 | 4.45 ± 1.03 | 9.66 ± 0.97 |
rq | −1.37 ± 0.62 | −1.57 ± 0.95 | −1.59 ± 1.06 | −1.91 ± 0.88 | −4.20 ± 0.88 | 2.53 ± 0.74 |
rL | −2.60 ± 0.77 | −4.05 ± 0.83 | −3.98 ± 0.91 | −4.51 ± 0.93 | −5.83 ± 1.04 | −1.37 ± 1.27 |
rMD | −2.76 ± 0.81 | −4.33 ± 0.85 | −4.30 ± 0.96 | −4.84 ± 1.00 | −6.08 ± 1.11 | −1.84 ± 1.34 |
rAD | −2.41 ± 0.70 | −3.63 ± 0.80 | −3.54 ± 0.83 | −4.14 ± 0.82 | −5.68 ± 0.96 | −0.87 ± 1.08 |
rRD | −3.04 ± 0.92 | −4.89 ± 0.92 | −4.92 ± 1.12 | −5.40 ± 1.17 | −6.37 ± 1.26 | −2.59 ± 1.57 |
*DTI metrics were defined as rX = (Xipsilateral − Xcontralateral) / Xcontralateral, where X indicates value of indices (mean ± standard error of the mean). DTI = diffusion tensor imaging, IC = infarct core, NT = normal tissue, rAD = relative axial diffusivity, rFA = relative fractional anisotropy, rL = relative diffusion magnitude, rMD = relative mean diffusivity, rq = relative pure anisotropy, rRD = relative radial diffusivity, TP = true penumbra