Table 2.

Classification performance in the validation set (n=134)

Algorithm	Stroke*	No stroke	Sensitivity	Specificity	PPV	AUC
Tirschwell and Longstreth#			0.889 (0.81–0.96)§	0.83 (0.76–0.90)	0.727 (0.62–0.84)
Longitudinal cohort	P‡>0.5	P<0.5	0.844 (0.75–0.94)	0.875 (0.82–0.93)	0.776 (0.68–0.87)	0.926 (0.89–0.96)
Case–control	P≥0.75	P≤0.15	0.906 (0.81–0.97)	0.946 (0.90–0.99)	0.879 (0.78–0.97)	0.948 (0.90–0.98)

Notes:

^*Decision rule for classifying acute ischemic stroke;

^#from Tirschwell and Longstreth;⁷

^‡predicted from classification model;

^§performance measure (bootstrapped 95% CI).

Abbreviations: PPV, positive predictive value; AUC, area under the curve.