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. 2018 Oct 18;13:6585–6602. doi: 10.2147/IJN.S178819

Figure 12.

Figure 12

Statistical analysis of IHC intensity scores of rats paw skin.

Notes: (A) TNF-α in thin skin, (B) TNF-α in thick skin, (C) caspase-3 in thin skin, and (D) caspase-3 in thick skin. Data are means ± SEM, n=6; statistical differences at P<0.05 considered significant; *vs normal control group; #vs positive control group; $vs 100 mg/kg Dcn-pretreated group.

Abbreviations: TNF-α, tumor necrosis factor-alpha; Dcn, diacerein; Glc, gelucire 44/14; TPGS, d-α-tocopheryl polyethylene glycol 1,000 succinate; SNEDDS, self-nanoemulsifying drug-delivery system; IHC, immunohistochemistry.