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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Adv Exp Med Biol. 2018;1072:405–411. doi: 10.1007/978-3-319-91287-5_65

Table 2.

Oxygen permeability (mean ± SD), partitioning, and related values.

System PM (cm/s) a aLb PL (cm/s)c h | l (nm)d 〈S〉e- KPf DM(×10−6 cm2/s)g
POPC 53 ± 2 1 53 ± 2 5.6 | 7.1 0.19 7.8 3.8
POPC/Chol 42 ± 2 1 42 ± 2 6.2 | 9.4 0.38 5.6 4.7
K+chan/POPC 24 ± 1 0.77 31 ± 1 6.2 | 8.4 0.23 6.6 2.3
K+chan/POPC/Chol 23 ± 1 0.73 32 ± 2 5.8 | 9.0 0.34 5.5 2.4
K+chan/KCl/POPC 29 ± 2 0.77 37 ± 2 6.2 | 8.4 0.22 7.7 2.3
a

Whole-membrane permeability, estimated according to Eq. 2, as in our prior work [11].

b

Fractional area occupied by lipid.

c

Actual or apparent permeability of the lipid bilayer region, estimated from Eq. 3.

d

Membrane thickness, h, based on O2 free energy profiles, determined as in [11] (data not shown). Average total box length, l, normal to the bilayer (standard deviation = 0.1 nm).

e

Average lipid order parameter for carbons 4-8 of all POPC palmitoyl tails, as described in [17].

f

Membrane/water O2 partition coefficient, from depth-dependent O2 distribution profiles, averaged over the whole membrane.

g

Apparent whole-membrane diffusion coefficient, estimated from the relation in Eq. 1.