Table 1.

Comparison of age, gender, BMI, HAMD-17 scores, plasma nesfatin-1, cortisol, IL-6, CRP, and TNF-α of MSDD group and control group (mean ± SEM)

Variables	Control group	MSDD group	Statistics (t or c2)	P-value
Age	34.81±12.19	35.86±15.78	−0.438	0.662
Gender (female/male)	39/31	35/35	0.459a	0.498
BMI (kg/m2)	23.34±1.67	23.29±1.44	0.206	0.837
HAM-D	6.60±3.10	27.41±11.92	−14.144	<0.01b
Nesfatin-1 (ng/mL)	0.83±0.16	1.61±0.29	−19.349	<0.01b
Cortisol (nmol/L)	196.78±102.76	431.55±85.50	−14.694	<0.01b
IL-6 (pg/mL)	59.50±13.17	66.65±6.78	−4.037	<0.01b
CRP (mg/L)	2.48±0.29	2.66±0.25	−3.87	<0.01b
TNF-α (ng/L)	167.15±27.82	168.92±18.29	−0.445	0.657

Notes:

^aShows χ² score.

^bP<0.01 was considered statistically significant.

Abbreviations: BMI, body mass index; CRP, C-reactive protein; HAM-D, Hamilton Depression Rating Scale; MSDD, moderate and severe depressive disorder; TNF-α, tumor necrosis factor-α.