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. Author manuscript; available in PMC: 2018 Oct 25.
Published in final edited form as: J Am Coll Cardiol. 2018 Jul 31;72(5):518–530. doi: 10.1016/j.jacc.2018.04.083

TABLE 3.

Baseline Characteristics (PHIV With HFpEF)

HfpEF on PI
(n = 57)
HfpEF on NPI
(n = 115)
p Value
Female 24 (43) 56 (49) 0.415
BMI, kg/m2 28.0± 5.6 27.0± 5.6 0.272
Age, yrs 60.0± 9.0 60.0± 9.4 0.994
Race
 Hispanic 19 (34) 35 (30) 0.701
 African American 26 (46) 49 (43)
 Others 12 (21) 31 (27)
CV risk factors
 Diabetes 26 (45) 40 (35) 0.169
 Hypertension 36 (64) 64 (56) 0.348
 Hyperlipidemia 31 (54) 40 (35) 0.014
 Smoking 20 (35) 59 (51) 0.044
CAD 28 (49) 33 (29) 0.008
Myocarditis 8 (14) 13 (11) 0.626
Cocaine 26 (46) 32 (28) 0.020
SBP, mm Hg 144.0± 25.8 141.0± 26.6 0.483
DBP, mm Hg 78± 18.8 79± 18.2 0.737
Heart rate, beats/min 80.0± 23.2 82.0± 22.7 0.590
PASP, mm Hg 47.0± 9.9 40.0± 8.1 <0.001
LVEF, % 57.0± 5.3 56.0± 5.0 0.231
SA 16 (28) 36 (31) 0.663
HCV 11 (20) 25 (22) 0.711
HIV parameters
 CD4 count at 1st HF admission, cells/mm3 276± 215 291± 193 0.645
 Nadir CD4 count, cells/mm3 218± 185 272± 191 0.080
 VL <200 copies/ml 34 (60) 72 (63) 0.707
 Duration of ART, yrs 8 (4–14) 9 (4–14) 0.842
 Duration of PI, yrs 6 (4–11)
 Duration of HIV* 8 (4–14) 9 (4–14) 0.842
 Duration of untreated HIV 75 (46–104) 74 (46–106) 0.632
Socioeconomic parameters
 High school or GED completion 38 (66) 72 (63) 0.601
 Unemployment 7(13) 14 (12) 0.983
ART medications
 NRTIs 57 (100) 115 (100) >0.05
 INSTIs 3(5) 44 (38) <0.001
 NNRTIs 4(7) 71 (62) <0.001
HF medications
 Beta-blocker 48 (85) 102 (89) 0.468
 ACE inhibitor or ARB 47 (83) 99 (86) 0.651
 Spironolactone 0(0) 0(0)
 Furosemide 39 (69) 92 (80) 0.093

Values are n (%), mean± SD, or median (interquartile range). Bold p values are statistically significant.

*

Duration of HIV is in years.

Duration of untreated HIV is the duration before starting ART after the diagnosis in days.

HFpEF = heart failure with preserved ejection fraction; other abbreviations as in Table 1.