Table 2.
Odds ratio (OR) according to quintiles of percentage of African ancestry in the Black Women Health’s Study
| Quintiles of percentage of African ancestry (range) | P-trend | Per 10% increase of African ancestry |
|||||
|---|---|---|---|---|---|---|---|
| Q1 (≤69.3) | Q2 (69.3–77.5) | Q3 (77.6–82.5) | Q4 (82.6–86.7) | Q5 (>86.7) | |||
| All women | |||||||
| Cases/controls | 377/517 | 492/525 | 549/515 | 564/508 | 650/531 | ||
| Basic1 | 1.00 (reference) | 1.35 (1.12–1.62) | 1.56 (1.30–1.88) | 1.63 (1.35–1.95) | 1.75 (1.46–2.09) | <0.0001 | 1.20 (1.14–1.26) |
| + SES2 | 1.00 (reference) | 1.28 (1.06–1.54) | 1.44 (1.20–1.74) | 1.49 (1.23–1.79) | 1.57 (1.31–1.89) | <0.0001 | 1.16 (1.10–1.22) |
| + BMI3 | 1.00 (reference) | 1.22 (1.00–1.49) | 1.38 (1.14–1.69) | 1.33 (1.09–1.62) | 1.41 (1.16–1.71) | <0.0001 | 1.12 (1.06–1.18) |
| Non-obese4 | |||||||
| Cases/controls | 121/367 | 154/328 | 175/318 | 173/303 | 191/306 | ||
| Multivariate5 | 1.00 (reference) | 1.44 (1.06–1.95) | 1.75 (1.30–2.36) | 1.55 (1.15–2.10) | 1.67 (1.24–2.25) | <0.0001 | 1.20 (1.10–1.30) |
| Obese4 | |||||||
| Cases/controls | 256/150 | 338/197 | 374/197 | 391/205 | 459/225 | ||
| Multivariate5 | 1.00 (reference) | 1.01 (0.77–1.33) | 1.11 (0.84–1.46) | 1.11 (0.84–1.45) | 1.15 (0.88–1.50) | 0.23 | 1.05 (0.97–1.13) |
1
Adjusted for age and geographic region of residence
2
Quintiles of neighborhood socioeconomic status, and years of education
3
Body mass index as a continuous variable
4
Non-obese, BMI<30 kg/m2; obese, BMI≥30 kg/m2
5
Adjusted for age, geographic region of residence, neighborhood socioeconomic status, years of education, and BMI (continuous)