TABLE 2.

Admit Multiple Electrode Platelet Aggregometry

	N=233	Manufacturer Normal Ranges
ADP AUC (U)	60 (47–71)	36–101
Low ADP Response (%)	10%	n/a
Collagen AUC (U)	49 (39–61)	24–79
Low Collagen Response (%)	4%	n/a
TRAP AUC (U)	97 (82–112)	75–137
Low TRAP Response (%)	17%	n/a
AA AUC (U)	61 (48–71)	42–100
Low AA Response (%)	18%	n/a
Ristocetin AUC (U)	66 (42–87)	27–124
Low Ristocetin Response (%)	13%	n/a
Overall Low Platelet Response (%)	36%	n/a

^*Data reported as median with inter-quartile ranges. Platelet aggregation was induced by agonist stimulation with adenosine diphosphate (ADP, via P2 receptors), collagen (via GpIa/IIa and GpVI receptors), thrombin receptor activating peptide-6 (TRAP, via PAR receptors), arachidonic acid (AA, via the cyclooxygenase pathway), or ristocetin (via vWF complex). Platelet adhesion to the electrodes was detected as increasing electrical impedance, measured by duplicate sets of sensor wires in each test cell. Platelet aggregation responses to multiple electrode platelet aggregometry are reported as area under the aggregation curve in units (U) over a 6-minute measurement period. p-values bolded for <0.05