Figure 1:

Overview of Experimental Design. In Arm 1 (blue box), individual MRI-to-CBCT rigid registrations were performed and GTVs were contoured for each successive scan (depicted in green). In Arm 2 (Green Box), MRI-to-CBCT fusion and GTV contouring were performed using Scan A. Velocity-based adaptive registration of CBCTs from Scan A to B and Scan A to C were performed to generate Velocity-adapted GTVs for Scans B and C (red).